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Use of "ice", MST or other methylated substances is another means of increasing the potency of marijuana, a method shared by methamphetamine users. This is not to be confused with the harsh method, crushing large rocks, which is used on much stronger "dabs" or bacterial hydrocarbon crystals of the cannabis plant or its synthetic equivalents. "Meth use can lead to faster onset of psychosis, more cravings and possibly sleep and appetite problems ([112], Psychopharmacology, In press). "Some evidence suggests that meth use can lead to lower thresholds for other psychotic experiences, such as seeing or hearing things that are not there, and hearing frightening or repetitive thoughts or voices ([112], Psychopharmacology, In press). "It can lead to impairment of learning and memory, and there are correlations between Meth use and poorer performance on tests of attention, executive function and episodic memory ([112], Psychopharmacology, In press). "Meth use may also affect the processing of emotions, such as affective memory, or incidences of mood lability ([112], Psychopharmacology, In press). "At low to moderate doses of meth, people may feel more awake and able to think clearly, and may have a more positive attitude towards themselves and their situation, while higher doses may lead to talkativeness, euphoria, agitation, and psychosis. "The amount of meth users in this cohort reported ingesting about 10mg per day on average. "These are relatively small amounts compared to doses used for more dangerous stimulant drugs such as cocaine, or for drugs such as ecstasy or amphetamine."

Many users of methamphetamine smile and laugh a lot. This is not a sign of happiness and they are not usually happy. They may even say you are crazy if you ask why they seem so happy. They just seem that way. It is actually a nervous and extreme way for addicts to cope with withdrawal.

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